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Out of 117 men who were suitable for taking sildenafil, the acceptance of sildenafil as a treatment option is high, 98.3% (115/117). Sildenafil was successful in treating ED in 91.3% (84/92) of this study population. At the end of the study period, 79.7% (59/74) of men wanted to continue treatment with sildenafil. The side effect profile of sildenafil in this study would appear to be different from previous published data  in that the incidence of headache, flushing, dyspepsia and abnormal vision is higher, but in the absence of a control group the significance of this is uncertain. It must be noted that 13% of men who reported side effects at Visit 2 reported complete lack of them at Visit 3. It is of interest that there is a 2% incidence each of thirst and 'dazed feeling' (reported by patients as a 'muzzy head'). The physiology underlying this is unclear, although it could be related to PDE inhibition in the brain, where the various PDE isoenzymes are in abundance . The researchers were scheduled to present their work Sept. 24 at the American Heart Association's conference on high blood pressure research in Chicago. Drugs such as sildenafil (Viagra), vardenafil (Levitra) or tadalafil (Cialis), Diabetes mellitus Buy viagra online NexMed, Inc. (Nasdaq: NEXM), a specialty CRO and a developer of products based on the NexACT® technology, announced today that it received a Notice of Non-Compliance ("Notice") as part of the review process from Health Canada for its New Drug Submission ("NDS") for the Vitaros erectile dysfunction treatment filed in February 2008. The deficiencies cited related to the product's CMC (Chemistry, Manufacturing and Controls). There were no pre-clinical or clinical deficiencies cited in the Notice. The Notice is a routine end-of-review communication from Health Canada when additional information is needed to reach final decision on product approval. Jason L Iltz, PharmD PDE-5 selective inhibitor. 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Sand MS, Fisher W, Rosen R, Heiman J, and Eardley I. Erectile dysfunction and constructs of masculinity and quality of life in the multinational Men's Attitudes to Life Events and Sexuality (MALES) study. J Sex Med 2008;5:583-594. To add to the problem, the penis contains much smaller blood vessels than the ones that carry blood to the heart and the brain, which is why men who have early heart disease may see the effects first in their penis and then in larger blood vessels. "Prostate cancer is very survivable," said Dr. Terry Mason, commissioner of the Chicago Department of Public Health and a volunteer member of the American Cancer Society Prostate Cancer Advisory Group. "It's a very treatable disease." Even someone who is a healthy individual might suffer from erectile dysfunction anxiety or impotence anxiety. Medical drugs specifically targeting your condition will greatly scale back the problem, generally however it may not necessarily eliminate it.
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